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br Material and methods br Results Consistent with our previ
2022-05-31

Material and methods Results Consistent with our previous study, SR-SIM and confocal microscopy showed a large number of IBA1-expressing AZD7687 australia in all parts of the human cochleae (Fig. 1). IBA1, the microglial and macrophage-specific calcium-binding protein, is involved in the membr
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In vertebrates three cognate receptors or
2022-05-31

In vertebrates, three cognate receptors or receptor-like sequences have been identified with distinct distributions and functions (Millar, 2005, Neill et al., 2001). Only two types of GnRHR occur in mammals, though (Morgan and Millar, 2004). The mammalian type I GnRHR shares over 80% amino cdk9 inhi
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Mongolian gerbils Meriones unguiculatus a social rodent spec
2022-05-31

Mongolian gerbils (Meriones unguiculatus), a social rodent species, are widely distributed in the typical steppe, desert steppe and desert habitats of northern China, Mongolia, and Trans-Baikal region of Russia. In wild, the recorded maximum lifespan (apparent longevity) was 29.5 months for female M
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alzheimer's disease Introduction Human pathogenic Leishm
2022-05-31

Introduction Human pathogenic Leishmania protozoa comprise 20 different species that are distributed throughout the world and cause the disease leishmaniasis [1]. Transmission primarily occurs through the bite of a female sand fly and clinical manifestations of the disease span from cutaneous lesio
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br Xenobiotics and the Glucocorticoid Receptor br Conclusion
2022-05-31

Xenobiotics and the Glucocorticoid Receptor Conclusion Transparency document Acknowledgements The author wishes to thank Professor Wilhelm Engström from the Swedish University of Agricultural Sciences (Department of Biomedical Sciences and Veterinary Public Health) for his proof reading
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Some of the key aspects of
2022-05-31

Some of the key aspects of the myofibroblasts’ biology, including their signaling sensitivity and residual regenerative potential, are shaped by their origin. In this respect, lineage studies on myofibroblast precursors are critical for increasing our understanding of the natural history of fibrosis
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In sharp contrast to these
2022-05-31

In sharp contrast to these genetically altered animals, there are two types of living fish that appear to lack Band 3 in their red blood cells. These are the Lamprey [45] and the Hagfish [46,47]. While these fish normally occupy their respective niches, the presumed compensatory mechanisms, as with
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When PKC was applied alone it attenuated
2022-05-31

When PKC19–31 was applied alone, it attenuated the activity run-down following excision. Furthermore, the activity induced by addition of PKC19–31 during PMA treatment in many cases was higher than in controls. Accordingly, in our experimental conditions, the mechanism which underlays channel inhibi
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In total strains with relatively rapid acid producing
2022-05-31

In total, 5 strains with relatively rapid acid-producing ability (MA14, 15M2, DQHXNQ38–12, 5G2, and 6G5) were selected for further analysis. Compared with the strains ATCC19435, ZN8, and D-XJ4–12, which were used as controls, these 5 strains exhibited significantly different growth and titratable ac
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br Conclusions br Introduction Bioinformatics analysis shows
2022-05-31

Conclusions Introduction Bioinformatics analysis shows that there are about 300,000 G-rich sequences in human genome if searching with the consensus sequence (G3+N1-7G3+N1-7G3+N1-7G3+) [1], and their localizations are non-random. These G-rich sequences always localize in functional regions, su
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We detected the FFAR protein with a molecular mass
2022-05-30

We detected the FFAR2 protein with a molecular mass of about 50 kDa, which is comparable to the main band detected in pigs (Li et al., 2014) but different from the calculated size based on the sequence (Wang et al., 2009). The size difference can be explained, at least in part, by glycosylation site
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Indeed another recent study found that the HR like cell
2022-05-30

Indeed, another recent study found that the HR-like cell death triggered in rice epidermal cells by an avirulent or incompatible isolate of the fungal pathogen , which causes blast disease, is a ferroptotic cell death phenomenon (). Similar to the heat shock example given above, elevated levels of
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We have presented evidence that only muscle FBPase is detect
2022-05-30

We have presented evidence that only muscle FBPase is detectable within HL-1 cells. This is consistent with past findings of the Eschrich's group, which showed that in rat heart 4-P-PDOT expression of FBPase is almost exclusively limited to the muscle isozyme [3]. Results of our preliminary experi
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The above inferences concluded that histidine is enhancing t
2022-05-30

The above inferences concluded that histidine is enhancing the overall stability and rigidity of the protein which further might be restraining the protein during the transition from inactive to active state and vice-versa present in the SANT domain. Since the SANT domain binds with histone via elec
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chemical m receptor EZH can also interact with Ten Eleven Tr
2022-05-30

EZH2 can also interact with Ten-Eleven Translocation gene family members (TET1, TET2, and TET3), which convert 5-methylcytosine (5 mC) to 5-hydroxymethylcytosine (5hmC), to cause changes in patterns of histone methylation and DNA methylation [52]. Huang et al. found that the expression levels of all
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