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On the contrary evidence also suggests that autophagy plays
2023-10-10
On the contrary, evidence also suggests that autophagy plays a striking protective role in cancer cells. Highly burgeoning cancer KJ Pyr 9 require cellular building blocks for their metabolism and energy production. At this stage of cancer development, autophagy acts as a friend providing all the e
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br Introduction Cadmium is a major component of heavy
2023-10-10
Introduction Cadmium is a major component of heavy metal pollution. Phytoremediation is considered to be the more effective method for recovering contaminated soil [[1], [2], [3], [4]] via cadmium absorption, transport, and accumulation. Several cadmium-associated proteins have previously been we
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The first objective of the present study
2023-10-10
The first objective of the present study was to investigate the impact of ageing on arginase activity in tissues which exhibit age-related impairments in their function. The second objective was to determine whether l-arginine supplementation modulated the effect of ageing on arginase activity. The
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To the best of our knowledge there
2023-10-10
To the best of our knowledge, there have been only a few reports on antiangiogenic activities about C. sanki, and its antiangiogenic constituents as well as its mechanism of action are worthy of further exploring and studying. Therefore, we carried out a bioassay-guided investigation of C. sanki in
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br Introduction Breast cancer is the second most lethal
2023-10-10
Introduction Breast cancer is the second most lethal cancer among women, accounting for approximately 40,000 deaths in the United States in 2015 [1]. The prognosis of breast cancer has improved significantly with the identification of immunohistochemical subtypes that predict response to therapy
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Elevated aminopeptidase activities were often detected in or
2023-10-10
Elevated aminopeptidase activities were often detected in organs of plant with accelerated protein turnover, such as leaves and petals during senescence, fruits maturation or in germinating seeds [22]. Moreover, it was proven that these enzymes take part in defense responses [[23], [24], [25]]. Part
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The direction of glutamate transport by the cell
2023-10-10
The direction of glutamate transport by the cell membrane transporter is reversible. As mentioned above, glutamate transport is an electrogenic process associated with a transmembrane ion gradient established by the Na+-K+ pump through hydrolysis of adenosine triphosphate. Under conditions of energy
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Adiponectin also works on AdipoR inducing extracellular Ca i
2023-10-10
Adiponectin also works on AdipoR1, inducing extracellular Ca2+ influx necessary for activation of Ca2+/calmodulin-dependent protein kinase kinase (CaMKK)β, AMPK (Fig. 1). This step is then followed by activation of SirT1 and increased expression and decreased acetylation of PPARγ coactivator (PGC)-1
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In this study we obtained the absorbance
2023-10-09
In this study, we obtained the absorbance and photoluminescence (PL) of Fenofibric acid receptor polymerized with various types of actin-binding proteins in order to probe the actin structures in situ without labeling. Both optical measurements have been useful in examining biomaterials such as DNA
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In addition we performed Western blot analysis of different
2023-10-09
In addition, we performed Western-blot analysis of different areas of mouse brain with Vincristine against mAck1 (Ureña et al., 2005). The data obtained showed a high rate of expression in neocortex, hippocampus, cerebellum, and brainstem (Fig. 4). More moderate levels of expression were seen in hy
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Given that there are substitutions between Anc and the
2023-10-09
Given that there are 132 substitutions between βAnc and the human β subunit, we wondered whether βAnc could replace the human β subunit in hybrid AChRs formed from ancestral and human subunits. We first confirmed that the β subunit is required for expression of human AChRs in HEK293 BI-7273 by co-tr
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The diagnosis of ICP is currently based on the
2023-10-09
The diagnosis of ICP is currently based on the presence of pruritus, raised fasting serum TBS levels above 10μmol/L, and/or elevated serum transaminases (in the absence of diseases that cause cholestasis or pruritus) as well as spontaneous relief of signs and symptoms within four to six weeks after
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br Introduction Lung cancer is the leading
2023-10-09
Introduction Lung cancer is the leading cause of cancer death worldwide and is one of the most refractory of solid tumors along with pancreatic cancer. Since 1975 there have been notable improvements in the 5-year survival rate of patients with lung cancer [1]. This improvement in survival is tho
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The phylogenetic relationship demonstrates that both bovine
2023-10-09
The phylogenetic relationship demonstrates that both bovine and porcine 12/15-LO is more related to the human enzyme than the rabbit enzyme, despite the fact that the rabbit reticulocyte enzyme is a 15-lipoxygenase. The rabbit is one single species that expresses a 12/15 LO with 15-LO activity while
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This project was funded by the University of the
2023-10-09
This project was funded by the University of the Philippines Diliman through the Natural Sciences Research Institute with grant No. CHE-09-2-02. Introduction There is compelling evidence for an anti-inflammatory effect of 12- and 15-lipoxygenases through the generation of lipid mediators involve
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