• In another approach to mediatorless sensors recombinant form

  2018-10-30

  

  In another approach to mediatorless sensors, recombinant forms of HRP were directly bound to polycrystalline gold to fabricate a hydrogen peroxide sensor [3]. It was shown that gold electrodes with recombinant HRP exhibited good electron transfer and produced sensitive and stable responses to hydrog

• br Results and discussion br Conclusion The quadruple

  2018-10-30

  

  Results and discussion Conclusion The quadruple dye labelled dual oxygen and pH-sensitive ratiometric nanosensors detailed in this article are capable of measuring dissolved oxygen concentrations, from 0 to 100%, and the full physiological sphingosine ranges from pH3.5 to 7.5. We envisage tha

• br Econom a del conocimiento y trabajadores del

  2018-10-30

  

  Economía del conocimiento y trabajadores del conocimiento La etapa actual, dominada por las tecnologías de la información y la comunicación, se basa en una utilización cada vez más intensiva del conocimiento útil con fines de producción de riqueza o más exactamente de rentas económicas. Ese es pr

• Bombardier Concarril se instal en el

  2018-10-30

  

  Bombardier-Concarril se instaló en el Complejo Industrial Sahagún aprovechando la red de proveedores altamente especializados desarrollada por Concarril desde los años setenta. A inicios de la década de los noventa Plásticos Automotrices Dina (más tarde Plásticos Automotrices Sahagún) y Siderúrgica

• By contrasting the issues in

  2018-10-30

  

  By contrasting the issues in this literature with the ones of structural breaks, Luporini (1999) contributes to the debate by investigating the performance of the Brazilian fiscal policy by dividing the original sample into sub-periods, according to the occurrence of changes in the debt/GDP ratio. I

• Using the IPEA DATA the five macro socioeconomic variables

  2018-10-30

  

  Using the IPEA/DATA, the five macro-socioeconomic variables were: the homicide and suicide rate per 100,000 inhabitants, the percentage of poor people, the Gini index as an income inequality measurement, the open unemployment rate and government expenses. These macro-variables were disaggregated for

• The essential autophagy gene beclin BECN is a

  2018-10-30

  

  The essential autophagy gene beclin 1 (BECN1) is a haploinsufficient tumor suppressor (Liang et al., 1999; Qu et al., 2003; Yue et al., 2003) that is also located on the breast cancer tumor susceptibility chromosomal locus 17q21, ~150kb centromeric to BRCA1 (Aita et al., 1999). Monoallelic loss of B

• Interrogating the underlying pathophysiology prior to

  2018-10-30

  

  Interrogating the underlying pathophysiology prior to the full-blown manifestations can help clarify some confounding effects. For example, extant neuroimaging research on established BP has suggested that the volume of gray matter (GM) decreases in the regions underpinning emotion processing and re

• We have presented data showing the

  2018-10-30

  

  We have presented data showing the discovery proteomic identification of three plasma proteins which are putative predictive marker of survival for SqCC NSCLC patients after radiotherapy. The level of two of these proteins (LRG1 and CRP) has been shown to be predictive with regard to survival, with

• noradrenaline This study has highlighted the complexity of o

  2018-10-30

  

  This study has highlighted the complexity of operationally defining compensation in neurodegenerative diseases such as HD. The previous literature in HD has thus far failed to address this issue, instead making assumptions of putative compensation based solely on increased activation or connectivity

• Petrovics et al demonstrated that

  2018-10-30

  

  Petrovics et al. demonstrated that the statistical power can be improved by combining and integrating different data types including whole genome sequencing (WGS), FISH assays and SNP array data. Despite the initial discovery was based on only 7 CA and 7 AA tumor/normal pairs of WGS data, the findin

• br Materials and Methods br Results br Discussion The presen

  2018-10-30

  

  Materials and Methods Results Discussion The present study demonstrated that both rs6435156C>T and rs1048829G>T variant genotypes in the 3′UTR of BMPR2 were associated with increased risk of COPD in a southern Chinese population. COPD smokers carrying the T variant (CT and TT) of rs6435156

• Givinostat Comparing cognitive and clinical measures across

  2018-10-30

  

  Comparing cognitive and clinical measures across all case groups and controls (Table 2) showed group effects for all measures, except physical anhedonia, and WAIS Perceptual Organization, Verbal Comprehension, and Working Memory indexes. Examining symptoms among case groups showed significant effect

• In this study we modeled VC to

  2018-10-30

  

  In this study, we modeled VC to project DEP in Europe given changes in climate. Throughout this study, we have included DTR in all of our VC calculations. We expanded our previous relative VC model to VC, by including temperature dependent dynamics in the female vector-to-human population ratio (Li

• The simultaneous analysis of ATI and FC levels shows that

  2018-10-29

  

  The simultaneous analysis of ATI and FC levels shows that the therapeutic escalation is associated to high values of either these variables. Importantly, their impact in the need of a future therapeutic escalation is independent of the disease severity, as is shown by the fact that neither histologi

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