• Adolescent neural development of emotional attentio http www

  2018-11-07

  

  Adolescent neural development of emotional attention has been initially investigated by a handful of cross-sectional studies. For negative distractors two studies suggest ongoing development of prefrontal regions: Monk et al. (2003) reported lower ACC activation in adults compared to adolescents for

• br Materials and methods br Results The statistical analyses

  2018-11-07

  

  Materials and methods Results The statistical analyses carried out in the present work generated a large number of results. Here we reported the main findings, and included some other results as in the supplementary text (e.g., age- and sex-related differences in GMD across the whole elastase

• So how exactly are growth mindsets

  2018-11-07

  

  So how exactly are growth mindsets linked with resilience to setbacks? Research has primarily focused on the associations between mindsets and motivational variables such as attributions and achievement goals to address this question (Dweck et al., 1995; Dweck and Leggett, 1988; Hong et al., 1999; M

• There are a number of potential

  2018-11-07

  

  There are a number of potential challenges in performing neuroimaging studies in a rural location in The Gambia, including transportation of the instrumentation, and introduction of experimental methods to a new Boc-Pro-OH and population of Africa infants. The portability of the fNIRS technology al

• br Methodology A case study approach was implemented to prov

  2018-11-06

  

  Methodology A case study approach was implemented to provide an in-depth analysis of the BIM-based sphingosine 1 phosphate receptor analysis and energy performance of buildings. This approach is supported (Naoum, 2007), which states that “case studies are used when a researcher intends to suppor

• br Disclosure of funding br Introduction

  2018-11-06

  

  Disclosure of funding Introduction Traumatic vorapaxar injury (TBI) is a common condition that leads to significant morbidity and mortality. Approximately 33–50% of acute TBI survivors will encounter emotional lability, such as post-traumatic agitation, characterized by aggression, akathisia,

• br Infection br Although treating spinal infections by

  2018-11-06

  

  Infection Although treating spinal infections by using MIS seems unfeasible because of their variable presentations and complicated course, the role of MIS in treating infections has recently been explored. In a retrospective case series of 21 patients with lumbar infectious spondylitis, the au

• Previous MCAO studies of MHP

  2018-11-06

  

  Previous MCAO studies of MHP36 candesartan cilexetil have used rats and assessed functional recovery using behavioural tasks (e.g. neurological severity score, rotational bias, spontaneous activity, bilateral asymmetry test, water maze). Improvement within six weeks after administration has been de

• nrf2 keap1 br Limitations Adenoviral infection was

  2018-11-06

  

  Limitations Adenoviral infection was performed 7days before FACS analysis. Due to constraints inherent in the hiPSC-CM differentiation system, the efficiency of adenoviral infection was not 100%. The percentages of the specific sub-populations reported do not take into account false negatives and

• This finding is consistent with our observations in

  2018-11-06

  

  This finding is consistent with our observations in human fetal RG cells (Mo and Zecevic, 2008), indicating that in both cell populations Pax6 affects proliferation as well as neuronal fate. Numerous studies have reported the successful transplantation of hESC into rodent brains (Kelly et al., 200

• Generally histone modifications facilitate protein protein i

  2018-11-06

  

  Generally, histone modifications facilitate protein–protein interactions with effector proteins or readers. Bromodomains interact with acetyl-lysines, while chromodomains, plant homeodomains (PHD), and others associate with methyl-lysines. Interestingly, H2AZ-containing nucleosomes associate with se

• We identified CaMKII as a downstream target of

  2018-11-06

  

  We identified CaMKII as a downstream target of NMDA receptors activated in NPCs following TLQP-62 treatment. CaMKII can associate with NMDA receptors and ultimately sustain its activation state (Bayer et al., 2001). Supporting our novel findings for a role of CaMKII in neurogenesis is a study showin

• As METH impairs self renewal capacity

  2018-11-06

  

  As METH impairs self-renewal capacity, we also explored the influence of METH in DG stem cell-fate division, a suitable method to characterize the phenotype of cells that are derived from the division of one DG stem cell. Indeed, a stem cell can undergo symmetric cell division towards self-renewal,

• Taken together we conclude that Lats may regulate adult

  2018-11-06

  

  Taken together, we conclude that Lats may regulate adult cardiomyocyte hypertrophy independent of Yap or Tead1. Rather than controlling cardiac hypertrophic growth, the canonical Hippo/Yap pathway is crucial for regulation of cardiomyocyte survival in the adult heart. This parallels the findings in

• br Materials and methods br Author disclosure

  2018-11-06

  

  Materials and methods Author disclosure statement Acknowledgments This work was supported by grants from the “Centro de Investigación Biomédica en Red en enfermedades raras” (CIBERER) (Grant 13-717/132.05 to RG), the “Instituto de Salud Carlos III” (FIS PI10/0703 and PI13/00556 to RG and PI

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